Seattle Seahawks vs. San Francisco 49ers picks, predictions NFL Week 2 – The Arizona Republic

The Seattle Seahawks and San Francisco 49ers play on Sunday in an NFL Week 2 game.
Which team will get the victory?
Check out these NFL Week 2 picks and predictions for the game, which can be seen at 1:05 p.m. MST on Fox.
The 49ers are an 8.5-point favorite in the game.
NFL Week 2 picks, predictions:
Jeremy Cluff writes: “The 49ers losing to the Bears in Week 1 was one of the big surprises of the NFL’s opening week of games. San Francisco should bounce back in Week 2 against the Seahawks.”
Bill Speros writes: “The learning curve for Trey Lance should be a bit straighter this week against the projected pasties of the NFC West. He and the Niners got washed out in Chicago Sunday. Seattle coach Pete Carroll turns 71 Thursday and will be coming off a Monday nighter against Russell Wilson.  If Lance struggles like he did in the Windy City rain, look for a shirtless Jimmy Garoppolo to come riding in on a white stallion to save the day.”
NFL Week 2 odds:
David Fucillo writes: “The 49ers struggled mightily in the rain, were without George Kittle, and lost Elijah Mitchell to injury. They should be able to beat Seattle, but with both Kittle and Mitchell in question for Week 2, this could be a grinder of a game. This pick also comes in before we see what the Seahawks look like on Monday against the Broncos. If they’re abysmal, this line could move a decent amount during and after MNF. If you think the Seahawks are the side, there might be some value waiting to see if the line moves even just a little with Monday’s game and/or 49ers injury updates.”
The site’s Football Power Index gives the Seahawks a 28.7% shot at picking up the victory.
More:NFL Week 2 schedule, television information: How to watch Week 2 NFL games
BJ Rudell writes: “If the 49ers lose this week, we’ll hear a lot of noise coming out of San Francisco. “Is Trey Lance ready?” I believe the team will step up big time at home against the beatable Seahawks, especially if George Kittle returns. Jeff Wilson Jr. is more than capable enough to handle RB duties in Elijah Mitchell’s absence, and the defense should be able to contain Geno Smith and Rashaad Penny more effectively than they did Justin Fields and the Chicago Bears’ middling backfield.”
Kyle Posey writes: “You all saw how many mistakes and miscues there were. I’d imagine the Niners come out ready to roll and will look to put it to Seattle. Plus, the Seahawks are an unknown. They’re trotting out new offensive linemen just as the 49ers did. The difference will be the defensive lines. It’s fair to assume Trey Lance and the offense will perform better under optimal conditions. We’ll see, but the sky isn’t falling based on the odds for next week.”
More:NFL power rankings Week 2: Cardinals, Bengals, Patriots, Packers plummet after Week 1 losses
Reach Jeremy Cluff at [email protected]. Follow him on Twitter @Jeremy_Cluff.
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